Antibody-functionality conjugates
Chemical conjugation is a versatile strategy that allows the generation of several different formats of BsAbs by using different crosslinkers. The crosslinkers contain several reactive groups which are used to conjugate the antibody units. Moreover, if there are additional reactive groups, they can be used to incorporate more functionalities such as fluorophores, simulating peptides, PEG, siRNA, cytotoxic drugs, etc.